CamStent

Camstent's solution to the problems of foreign body reaction and irritation, leading to excessive inflammation, and subsequent thrombus formation, is based on a polymer substrate that substitutes for the coating currently used in drug-eluting stents.  This version of the polymer is both oleophobic and hydrophobic, able to resist adhesion platelets and protein factors involved in clotting and subsequent thrombus formation.

‘Non-stick stents’, based on our proprietary coating, have five major advantages over current formulations because they are:

• Biologically inert: they don't exacerbate inflammation or carry risk of side-effects.
  
• Durable:  they remain part of stent surface, effective for the duration of the stent's life.
  
• Thin-Film:  their smooth coating decreases turbulence caused by surface roughness; a factor which has been implicated in coronary thrombosis.
  
• Non-pharmacologic:  they will not incur any drug-drug interactions with immunosuppressants already coupled to the stent. They don't require control of elution rates, control of characterisation or testing for drug stability, availability, release, or degradation.
  
• Localized effect: they can be applied preferentially to the luminal side of the stent, facing the blood stream, while the endothelial side can still be coated with a conventional drug-eluting combination, achieving an optimal combination of anti-stenotic and anti-thrombotic properties.